Autoimmune Disease: What It Is, How It Affects You, and What You Can Do

When your autoimmune disease, a condition where the immune system mistakenly targets healthy cells in the body. Also known as autoimmunity, it doesn’t just cause mild discomfort—it can break down joints, damage organs, and disrupt daily life. This isn’t a single illness. It’s a group of over 80 different conditions where your body’s defense system turns against you. Think of it like a security guard who starts locking you out of your own house—except instead of doors, it’s your skin, thyroid, joints, or nerves being targeted.

Common types include lupus, a systemic disease that can affect skin, kidneys, and blood vessels, rheumatoid arthritis, a chronic condition that attacks joint lining and causes pain and swelling, and multiple sclerosis, where the immune system damages the protective covering of nerve fibers. These aren’t rare. Millions live with them. And many of the medications used to treat them—like immunosuppressants, corticosteroids, or biologics—are designed to calm down that overactive immune response. But those drugs don’t come without risks. They can make you more vulnerable to infections, affect how other meds work, or cause long-term side effects like bone loss or liver stress.

What you might not realize is how closely autoimmune disease ties into other health issues you read about here. For example, autoimmune disease often leads to kidney damage, which shows up as protein in urine—a sign covered in our post on proteinuria. Some treatments increase bleeding risk, which connects to our guides on blood thinners and garlic supplements. Others interfere with absorption after surgery, or interact dangerously with common painkillers. Even sleep problems from medications like aripiprazole or melatonin can make autoimmune symptoms worse. It’s all linked.

You won’t find a cure in a pill. But you can find control. Through careful drug management, lifestyle tweaks, and knowing which supplements to avoid, many people stabilize their condition and live full lives. Below, you’ll find real-world advice on how medications interact with autoimmune conditions, what to watch for when your body changes, and how to avoid dangerous mix-ups that could set you back. This isn’t theory. It’s what people are dealing with right now—and what you need to know to stay safe.